Monday, April 11, 2011
Sunday, April 10, 2011
spirin or ibuprofen
sk
Published April 08, 2011
| Reuters
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A new study adds to growing evidence that regular use of painkillers like aspirin or ibuprofen may reduce a person's risk of developing colon or rectal cancers - sometimes by as much as 50 percent.
This latest report also shows that people with a family history of colon cancer - who are therefore at higher risk for the disease - also benefit from the pain relievers.
"The (risk) reductions that we saw here are not inconsequential," said Dr. Elizabeth Ruder of the National Cancer Institute, the study's lead author.
"But we're not at the point that one could make a public health recommendation" based on the findings, she added.
Colon and rectal cancers are diagnosed in about 48 out of every 100,000 people in the U.S., according to the National Cancer Institute.
Together, these "colorectal" cancers are the third-leading cause of deaths from cancer.
Previous studies have found that aspirin is tied to a smaller risk of colon cancer.
The current study expanded on earlier research by including larger numbers of people and assessing where in the colon cancers occurred.
Using questionnaire data from more than 300,000 adults, Ruder's group analyzed how often people took any of 19 non-steroidal anti-inflammatory (NSAID) pain medications, which include aspirin, ibuprofen (Advil), naproxen sodium (Aleve), sulindil (Clinoril), and others.
The observed drop in cancer risk varied depending on how often people took the painkillers and the type of cancer in question.
Overall, taking any of the NSAID drugs was associated with a 20 percent drop in the risk of colorectal cancer over 10 years.
And the more frequently people took a drug, the less likely they were to be diagnosed with colon or rectal cancer.
Daily use of an NSAID was associated with a 28 percent drop in colon cancer risk, for instance, whereas monthly use was associated with only a 14 percent reduction in risk.
A similar pattern was seen among people with immediate family members who had been diagnosed with colon cancer: Daily users of NSAIDs saw a 28 percent drop in their risk of colon or rectal cancer, and weekly users had an 11 percent decline.
When the researchers looked at the site in the colon where cancers appeared, the drugs' effects were more pronounced, but distinctly different for aspirin versus non-aspirin NSAIDs.
Those who took aspirin daily, for example, had a 62 percent drop in rectal cancer risk, but their risk of colon cancer did not change.
In contrast, non-aspirin NSAIDs, taken daily, were linked to a 56 percent drop in risk of colon cancers farthest from the rectum (a region called the proximal colon), whereas the risk of rectal cancer was unaffected.
Ruder said it's unclear why there's a difference between the type of drug and the risk of developing a particular type of colorectal cancer.
One of the limitations of the study, the authors note, is that they didn't monitor how long people took the drugs.
The researchers also caution that they did not weigh the potential benefits of the drugs against their drawbacks.
"There's an elevated risk of gastrointestinal ulcers and bleeds" from taking aspirin, said Amanda Cross, an investigator at the National Cancer Institute and another of the study's authors.
"We're certainly not advocating that people take aspirin to reduce the risk of colon cancer," she told Reuters Health.
The research, funded by the National Institutes of Health, is published in the American Journal of Gastroenterology.
Dr. Andrew Chan, a gastroenterologist at Massachusetts General Hospital who was not involved in the study, said it would be premature to offer any recommendations.
"I think what remains to be addressed," Chan said, "is, 'are there specific types of colon cancer that may be most likely to benefit from aspirin use, and who are the best patients to take aspirin?'"
Fewer studies supporting the use of non-aspirin NSAIDS in reducing colon cancer risk have been done, he added.
"This is an area of a lot of controversy," Chan told Reuters Health.
But the study is useful in backing up what doctors are beginning to realize, he said. "These are compelling data, which support (the idea) that aspirin use reduces the risk of colorectal cancer."
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Published April 08, 2011
| Reuters
Print Email Share Comments
Text Size
A new study adds to growing evidence that regular use of painkillers like aspirin or ibuprofen may reduce a person's risk of developing colon or rectal cancers - sometimes by as much as 50 percent.
This latest report also shows that people with a family history of colon cancer - who are therefore at higher risk for the disease - also benefit from the pain relievers.
"The (risk) reductions that we saw here are not inconsequential," said Dr. Elizabeth Ruder of the National Cancer Institute, the study's lead author.
"But we're not at the point that one could make a public health recommendation" based on the findings, she added.
Colon and rectal cancers are diagnosed in about 48 out of every 100,000 people in the U.S., according to the National Cancer Institute.
Together, these "colorectal" cancers are the third-leading cause of deaths from cancer.
Previous studies have found that aspirin is tied to a smaller risk of colon cancer.
The current study expanded on earlier research by including larger numbers of people and assessing where in the colon cancers occurred.
Using questionnaire data from more than 300,000 adults, Ruder's group analyzed how often people took any of 19 non-steroidal anti-inflammatory (NSAID) pain medications, which include aspirin, ibuprofen (Advil), naproxen sodium (Aleve), sulindil (Clinoril), and others.
The observed drop in cancer risk varied depending on how often people took the painkillers and the type of cancer in question.
Overall, taking any of the NSAID drugs was associated with a 20 percent drop in the risk of colorectal cancer over 10 years.
And the more frequently people took a drug, the less likely they were to be diagnosed with colon or rectal cancer.
Daily use of an NSAID was associated with a 28 percent drop in colon cancer risk, for instance, whereas monthly use was associated with only a 14 percent reduction in risk.
A similar pattern was seen among people with immediate family members who had been diagnosed with colon cancer: Daily users of NSAIDs saw a 28 percent drop in their risk of colon or rectal cancer, and weekly users had an 11 percent decline.
When the researchers looked at the site in the colon where cancers appeared, the drugs' effects were more pronounced, but distinctly different for aspirin versus non-aspirin NSAIDs.
Those who took aspirin daily, for example, had a 62 percent drop in rectal cancer risk, but their risk of colon cancer did not change.
In contrast, non-aspirin NSAIDs, taken daily, were linked to a 56 percent drop in risk of colon cancers farthest from the rectum (a region called the proximal colon), whereas the risk of rectal cancer was unaffected.
Ruder said it's unclear why there's a difference between the type of drug and the risk of developing a particular type of colorectal cancer.
One of the limitations of the study, the authors note, is that they didn't monitor how long people took the drugs.
The researchers also caution that they did not weigh the potential benefits of the drugs against their drawbacks.
"There's an elevated risk of gastrointestinal ulcers and bleeds" from taking aspirin, said Amanda Cross, an investigator at the National Cancer Institute and another of the study's authors.
"We're certainly not advocating that people take aspirin to reduce the risk of colon cancer," she told Reuters Health.
The research, funded by the National Institutes of Health, is published in the American Journal of Gastroenterology.
Dr. Andrew Chan, a gastroenterologist at Massachusetts General Hospital who was not involved in the study, said it would be premature to offer any recommendations.
"I think what remains to be addressed," Chan said, "is, 'are there specific types of colon cancer that may be most likely to benefit from aspirin use, and who are the best patients to take aspirin?'"
Fewer studies supporting the use of non-aspirin NSAIDS in reducing colon cancer risk have been done, he added.
"This is an area of a lot of controversy," Chan told Reuters Health.
But the study is useful in backing up what doctors are beginning to realize, he said. "These are compelling data, which support (the idea) that aspirin use reduces the risk of colorectal cancer."
Print Email Share Comments
Text Size
View ArticleLeave a CommentSort: NewestSort: OldestYou must login to comment.
View Article
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Saturday, April 9, 2011
longevity"
d !
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The New Anti Aging & Longevity Report 寄給 我
顯示詳細資料 4月4日 (5 天以前)
The New Longevity Report
The word "longevity" is sometimes used as a synonym for "life expectancy" in demography or to connote "long life", especially when it concerns someone or something lasting longer than expected (an ancient tree, for example).
Reflections on longevity have usually gone beyond acknowledging the brevity of human life and have included thinking about methods to extend life. Longevity has been a topic not only for the scientific community but also for writers of travel, science fiction, and utopian novels.
There are many difficulties in authenticating the longest human life span ever by modern verification standards, owing to inaccurate or incomplete birth statistics. Fiction, legend, and folklore have proposed or claimed life spans in the past or future vastly longer than those verified by modern standards, and longevity narratives and unverified longevity claims frequently speak of their existence in the present.
Longevity and lifestyle
Evidence-based studies indicate that longevity is based on two major factors, genetics and lifestyle choices. Twin studies, have estimated that approximately 20-30% of an individual’s lifespan is related to genetics, the rest is due to individual behaviors and environmental factors which can be modified. Study of the regions of the world known as blue zones, where people commonly live active lives past 100 years of age, have shown that longevity is related to a healthy social and family life, not smoking, eating a plant-based diet, frequent consumption of legumes and nuts, and engaging in regular physical activity. In another well-designed cohort st udy, the combination of a plant based diet, frequent consumption of nuts, regular physical activity, normal BMI, and not smoking accounted for differences up to 10 years in life expectancy. The Alameda County Study discovered three additional lifestyle characteristics that promote longevity: limiting alcohol consumption, sleeping 7 to 8 hours per night, and not snacking (eating between meals).
Longevity traditions are traditions about long-lived people (generally supercentenarians), and practices that have been believed to confer longevity. A comparison and contrast of "longevity in antiquity" (such as the Sumerian King List, the genealogies of Genesis, and the Persian Shahnameh) with "longevity in historic al times" (common-era cases through twentieth-century news reports) is elaborated in detail in Lucian Boia's 2004 book Forever Young: A Cultural History of Longevity from Antiquity to the Present and other sources.
The Fountain of Youth reputedly restores the youth of anyone who drinks of its waters. The New Testament, following older Jewish tradition, attributes healing to the Pool of Bethesda when the waters are "stirred" by an angel. After the death of Juan Ponce de León, Gonzalo Fernández de Oviedo wrote in Historia General y Natural de las Indias (1535) that Ponce de León was looking for the waters of Bimini to cure his aging. Traditions that have been believed to confer greater human longevity also include alchemy, such as that attributed to Nicolas Flamel. In the modern era, the Okinawa diet has some reputation of linkage to exceptionally high ages.
Recent increases in the rates of lifestyle diseases, such as obesity, diabetes, hypertension, and heart disease, may drastically slow or reverse this trend toward increasing life expectancy in the developed world.
Since 1840, record life expectancy has risen linearly for men and women, albeit more slowly for men. For women the increase has been almost three months per year. In light of steady increase, without any sign of limitation, the suggestion that life expectancy will top out must be treated with caut ion. Scientists Oeppen and Vaupel observe that experts who assert that "life expectancy is approaching a ceiling ... have repeatedly been proven wrong." It is thought that life expectancy for women has increased more dramatically owing to the considerable advances in medicine related to childbirth.
Some argue that molecular nanotechnology will greatly extend human life spans. If the rate of increase of life span can be raised with these technologies to a level of twelve months increase per year, this is defined as effective biological immortality and is the goal of radical life extension.
Human Growth Hormone Studies
Studies have shown that increased levels of Human Growth Hormone (HGH) may reverse biological aging. HGH is a natural hormone in the body produced by the Pituitary gland. After our teen years our bodies produce increasingly less HGH. This leads to increased body fat, decreased immunity, poor skin tone, decreased libido, and other symptoms usually associated with aging.Some increase in HGH levels can be achieved naturally by exercise, careful attention to diet, and reducing body weight to optimum levels.
Injections of pure HGH have been used to raise HGH levels but this is extremely expensive. Most of the supplements on the market today contain very low levels of HGH ( to keep the price low ) - too low to have any real, lasting effect.
Research indicates that the best way to elevate HGH levels is to stimulate the body to produce more HGH. Rather than introduce more HGH into the body, you can stimulate your own pituitary gland to produce more HGH.
In clinical trials increased HGH has been shown to give:
8.8% increase in muscle mass on average after six months, without exercise
14.4% loss of fat on average after six months, without dieting
Higher energy levels
Enhanced sexual performance
Regrowth of heart, liver, spleen, kidneys and other organs that shrink with age
Greater cardiac output
Superior immune function
Increased exercise performance
Better kidney function
Lowered blood pressure
Improved cholesterol profile, with higher HDL and lower LDL
Stronger bones
Faster wound healing
Younger, tighter, thicker skin
Hair regrowth
Wrinkle removal
Elimination of cellulite
Sharper vision
Mood elevation
Increased memory retention
Improved sleep
How Does HGH STIM Work ? It was originally believed that older pituitary glands didn't have the capacity to produce large amounts of HGH . HGH STIM is a sound frequency product that is belived to stimulate the pituitary gland. It can be used whilst awake or asleep.
For more information about this product click HERE
To find out more about the musical suite version of this product click HERE
For more Anti Aging & Longevity products click HERE
Personal Page SEO Systems
Morecambe
Lancaster, Lancashire
LA75OH
GB
If you no longer wish to receive communication from us:
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http://www.sanderlu.net/
收件匣
X
回覆
The New Anti Aging & Longevity Report 寄給 我
顯示詳細資料 4月4日 (5 天以前)
The New Longevity Report
The word "longevity" is sometimes used as a synonym for "life expectancy" in demography or to connote "long life", especially when it concerns someone or something lasting longer than expected (an ancient tree, for example).
Reflections on longevity have usually gone beyond acknowledging the brevity of human life and have included thinking about methods to extend life. Longevity has been a topic not only for the scientific community but also for writers of travel, science fiction, and utopian novels.
There are many difficulties in authenticating the longest human life span ever by modern verification standards, owing to inaccurate or incomplete birth statistics. Fiction, legend, and folklore have proposed or claimed life spans in the past or future vastly longer than those verified by modern standards, and longevity narratives and unverified longevity claims frequently speak of their existence in the present.
Longevity and lifestyle
Evidence-based studies indicate that longevity is based on two major factors, genetics and lifestyle choices. Twin studies, have estimated that approximately 20-30% of an individual’s lifespan is related to genetics, the rest is due to individual behaviors and environmental factors which can be modified. Study of the regions of the world known as blue zones, where people commonly live active lives past 100 years of age, have shown that longevity is related to a healthy social and family life, not smoking, eating a plant-based diet, frequent consumption of legumes and nuts, and engaging in regular physical activity. In another well-designed cohort st udy, the combination of a plant based diet, frequent consumption of nuts, regular physical activity, normal BMI, and not smoking accounted for differences up to 10 years in life expectancy. The Alameda County Study discovered three additional lifestyle characteristics that promote longevity: limiting alcohol consumption, sleeping 7 to 8 hours per night, and not snacking (eating between meals).
Longevity traditions are traditions about long-lived people (generally supercentenarians), and practices that have been believed to confer longevity. A comparison and contrast of "longevity in antiquity" (such as the Sumerian King List, the genealogies of Genesis, and the Persian Shahnameh) with "longevity in historic al times" (common-era cases through twentieth-century news reports) is elaborated in detail in Lucian Boia's 2004 book Forever Young: A Cultural History of Longevity from Antiquity to the Present and other sources.
The Fountain of Youth reputedly restores the youth of anyone who drinks of its waters. The New Testament, following older Jewish tradition, attributes healing to the Pool of Bethesda when the waters are "stirred" by an angel. After the death of Juan Ponce de León, Gonzalo Fernández de Oviedo wrote in Historia General y Natural de las Indias (1535) that Ponce de León was looking for the waters of Bimini to cure his aging. Traditions that have been believed to confer greater human longevity also include alchemy, such as that attributed to Nicolas Flamel. In the modern era, the Okinawa diet has some reputation of linkage to exceptionally high ages.
Recent increases in the rates of lifestyle diseases, such as obesity, diabetes, hypertension, and heart disease, may drastically slow or reverse this trend toward increasing life expectancy in the developed world.
Since 1840, record life expectancy has risen linearly for men and women, albeit more slowly for men. For women the increase has been almost three months per year. In light of steady increase, without any sign of limitation, the suggestion that life expectancy will top out must be treated with caut ion. Scientists Oeppen and Vaupel observe that experts who assert that "life expectancy is approaching a ceiling ... have repeatedly been proven wrong." It is thought that life expectancy for women has increased more dramatically owing to the considerable advances in medicine related to childbirth.
Some argue that molecular nanotechnology will greatly extend human life spans. If the rate of increase of life span can be raised with these technologies to a level of twelve months increase per year, this is defined as effective biological immortality and is the goal of radical life extension.
Human Growth Hormone Studies
Studies have shown that increased levels of Human Growth Hormone (HGH) may reverse biological aging. HGH is a natural hormone in the body produced by the Pituitary gland. After our teen years our bodies produce increasingly less HGH. This leads to increased body fat, decreased immunity, poor skin tone, decreased libido, and other symptoms usually associated with aging.Some increase in HGH levels can be achieved naturally by exercise, careful attention to diet, and reducing body weight to optimum levels.
Injections of pure HGH have been used to raise HGH levels but this is extremely expensive. Most of the supplements on the market today contain very low levels of HGH ( to keep the price low ) - too low to have any real, lasting effect.
Research indicates that the best way to elevate HGH levels is to stimulate the body to produce more HGH. Rather than introduce more HGH into the body, you can stimulate your own pituitary gland to produce more HGH.
In clinical trials increased HGH has been shown to give:
8.8% increase in muscle mass on average after six months, without exercise
14.4% loss of fat on average after six months, without dieting
Higher energy levels
Enhanced sexual performance
Regrowth of heart, liver, spleen, kidneys and other organs that shrink with age
Greater cardiac output
Superior immune function
Increased exercise performance
Better kidney function
Lowered blood pressure
Improved cholesterol profile, with higher HDL and lower LDL
Stronger bones
Faster wound healing
Younger, tighter, thicker skin
Hair regrowth
Wrinkle removal
Elimination of cellulite
Sharper vision
Mood elevation
Increased memory retention
Improved sleep
How Does HGH STIM Work ? It was originally believed that older pituitary glands didn't have the capacity to produce large amounts of HGH . HGH STIM is a sound frequency product that is belived to stimulate the pituitary gland. It can be used whilst awake or asleep.
For more information about this product click HERE
To find out more about the musical suite version of this product click HERE
For more Anti Aging & Longevity products click HERE
Personal Page SEO Systems
Morecambe
Lancaster, Lancashire
LA75OH
GB
If you no longer wish to receive communication from us:
Cancel
To update your contact information:
Update
http://www.sanderlu.net/
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